Function Health vs Marek Health
Function Health vs Marek Health: these two are built for different jobs. Function is broad preventive screening, $365 a year for 114 biomarkers drawn twice, at $3.20 per marker. Marek is built for hormone optimization and TRT: a narrower 56-marker panel at $495, but with sensitive estradiol, IGF-1, and fasting insulin, and clinicians who will actually prescribe and manage testosterone, which Function won't.
I've tested Function Health myself and reviewed Marek's panel, pricing, and care model on their own site. To compare the counts like for like I pulled each current list and normalized the marker names.
Below: pricing and cost per biomarker, the exact tests each includes and where they diverge, who founded each company, and the apps.
Function Health vs Marek Health: pricing
| Function Health | Marek Health | |
|---|---|---|
| Price | $365 | $495 |
| Cadence | Twice per year (Annual: 100+ tests, Follow-up: 60+ tests) | On-demand (pay per test) |
| Biomarkers | 114 | 56 |
| Cost per biomarker | $3.20 | $8.84 |
Cost per biomarker is the sticker price divided by the number of markers, a rough apples-to-apples figure. It ignores cadence, the app, and any doctor review, which the sections below cover.
Function Health vs Marek Health: biomarkers compared
Function Health's Annual Membership covers 114 biomarkers and Marek Health's Comprehensive covers 56. They share 46. 68 are unique to Function Health and 10 are unique to Marek Health.
Only in Function Health (68)
- ABO Blood Group
- Amylase
- Anti-Mullerian Hormone (AMH)
- Anti-Nuclear Antibodies Pattern
- Anti-Nuclear Antibodies Titer
- Antinuclear Antibodies (ANA)
- Arachidonic Acid/EPA Ratio
- Biological Age
- Cholesterol/HDL Ratio
- Estradiol (E2)
- Ferritin
- Homocysteine
- Iron
- Iron Saturation
- Large HDL Particles
- LDL Particle Number
- LDL Pattern
- LDL Peak Size
- Lead
- Leptin
- Lipase
- Lipoprotein (a)
- Magnesium
- Mean Corpuscular Volume (MCV)
- Mean Platelet Volume (MPV)
- Medium LDL Particles
- Mercury
- Methylmalonic Acid
- Non-HDL Cholesterol
- Omega-3 DHA
- Omega-3 DPA
- Omega-3 EPA
- Omega-3 Total
- Omega-6 Arachidonic Acid
- Omega-6 Linoleic Acid
- Omega-6 Total
- Omega-6/Omega-3 Ratio
- PSA Free
- PSA Percent Free
- PSA Total
- Red Cell Distribution Width (RDW)
- Rheumatoid Factor
- Selenium
- Small LDL Particles
- Thyroglobulin Antibodies
- Total Iron Binding Capacity
- Uric Acid
- Urine Amorphous Sediment
- Urine Appearance
- Urine Bacteria
- Urine Bilirubin
- Urine Blood
- Urine Calcium Oxalate Crystals
- Urine Color
- Urine Glucose
- Urine Hyaline Casts
- Urine Ketones
- Urine Leukocyte Esterase
- Urine Nitrite
- Urine pH
- Urine Protein
- Urine Red Blood Cells
- Urine Specific Gravity
- Urine Squamous Epithelial Cells
- Urine White Blood Cells
- Urine Yeast
- Vitamin D (25-Hydroxy)
- Zinc
Only in Marek Health (10)
- Estradiol, Sensitive/Ultrasensitive (LC/MS)
- Fasting Insulin
- hCG-Beta Subunit (Female)
- IGF-1 (Insulin-like Growth Factor 1)
- Immature Granulocytes
- LDL/HDL Ratio
- Neutrophil/Lymphocyte Ratio
- Progesterone
- Total Protein
- VLDL Cholesterol
Show the 46 biomarkers both include
- Alanine Aminotransferase
- Albumin
- Albumin/Globulin Ratio
- Alkaline Phosphatase
- Apolipoprotein B
- Aspartate Aminotransferase
- Basophils
- BUN (Blood Urea Nitrogen)
- BUN/Creatinine Ratio
- Calcium
- Carbon Dioxide (CO2)
- Chloride
- Cortisol
- Creatinine
- DHEA-Sulfate
- eGFR (Estimated Glomerular Filtration Rate)
- Eosinophils
- Follicle Stimulating Hormone (FSH)
- Free T3 (Triiodothyronine)
- Free T4 (Thyroxine)
- Free Testosterone
- Gamma-Glutamyl Transferase
- Globulin
- Glucose
- HDL Cholesterol
- Hematocrit
- Hemoglobin
- Hemoglobin A1c
- High-Sensitivity C-Reactive Protein
- LDL Cholesterol
- Luteinizing Hormone (LH)
- Lymphocytes
- Monocytes
- Neutrophils
- Platelet Count
- Potassium
- Prolactin
- Red Blood Cell Count
- Sex Hormone Binding Globulin (SHBG)
- Sodium
- Thyroid-Stimulating Hormone
- Total Bilirubin
- Total Cholesterol
- Total Testosterone
- Triglycerides
- White Blood Cell Count
Function Health vs Marek Health: founders and team
Function Health
Doctor on founding team? Yes
- Founded: 2021
- Funding: $800M+ raised; $450M growth financing (Jul 2026, General Catalyst's Customer Value Fund) on top of a $298M Series B (Nov 2025, led by Redpoint) at a $2.5B valuation
- Founders:
- Jonathan Swerdlin — Co-founder & CEO
- Mark Hyman, MD — Co-founder & Chief Medical Officerphysician
- Pranitha Patil — Co-founder & COO
- Mike Nemke — Co-founder & CTO
Physician co-founder Mark Hyman, MD is a functional-medicine doctor and serves as Chief Medical Officer.
Marek Health
Doctor on founding team? No
- Founded: 2020
- Founders:
- Derek (More Plates More Dates) — Co-founder
- Mike Stratton — Co-founder & CEO
Founder-owned with no announced venture funding, built off Derek's hormone-optimization audience. Marek employs MDs, DOs, and NPs, but the clinicians are staff, not founders.
Function Health vs Marek Health: apps and technology
| Function Health | Marek Health | |
|---|---|---|
| iOS app | ✓ | — |
| Android app | ✓ | — |
| Web app | ✓ | ✓ |
| Trained its own AI model | Announced a "Medical Intelligence" AI product (Nov 2025), but disclosed no model, paper, or architecture | — |
- Function Health: Function markets Medical Intelligence as proprietary AI, but has published no model card, paper, or named provider. It reads as an orchestration/RAG layer over existing LLMs plus its biomarker data; a genuine trained foundation model can't be verified from public sources.
- Marek Health: Web member portal only; no native mobile app or AI-model announcement found. Positioning is evidence-based protocols, not AI.
Function Health vs Marek Health: which is better?
For a broad once- or twice-a-year screen, Function is cheaper and covers nearly twice the markers. Choose Marek if your goal is hormone optimization or TRT and you want clinicians who prescribe and manage treatment, not just software that flags an out-of-range result.
Two things to weigh: Marek is web-only, with no iOS or Android app, and it's founder-owned, built off Derek (More Plates More Dates)'s hormone-optimization audience, with MDs, DOs, and NPs on staff but not among the named founders. Function has a physician co-founder in Mark Hyman, MD.