Nutrients
Homocysteine test cost: $22–$98
By Elo. Last updated September 1, 2026.
A Homocysteine test costs as little as $22 on its own, or $150–$275/mo in a 41-biomarker bundle. The lowest-cost providers of Homocysteine are Mito Health ($22–$28), DrSays ($44), and Ulta Lab Tests ($50). Every price on this page is an all-in total, list price plus whatever draw or physician fee the lab adds at checkout, because the advertised number usually leaves the fee out. Last checked July 2026.
Homocysteine is an amino acid linked to cardiovascular risk; elevated levels often reflect low B vitamins (B6, B9, B12).
Below: Homocysteine priced at every lab that sells it on its own, every panel we track that includes it, whether it's worth buying at all, and what insurance pays.
How much does a Homocysteine test cost?
Homocysteine costs $22–$98 on its own, or $275–$399 in a bundle. Those are cash prices, so that's also what Homocysteine costs without insurance.
Lowest Homocysteine self-pay prices
The lowest cash price we found for Homocysteine is $22–$28 at Mito Health, followed by DrSays ($44), Ulta Lab Tests ($50), Quest ($81), and Marek Diagnostics ($98). These are all-in prices that include the draw fee: Mito Health lists Homocysteine at $12.70 and adds a $9.50–$15 draw fee, for $22.20–$27.70 total.
Cost of Homocysteine in a bundle
Seven packages we track include Homocysteine, and every one of them tests dozens of other markers from the same draw. The cheapest bundle with Homocysteine is Parsley Health's 41-biomarker panel at $150–$275/mo, then Mito Health ($315 for 99 markers), Superpower ($349 for 59 markers), WHOOP Advanced Labs ($349 for 65 markers), Function Health ($365 for 114 markers), Vitals Vault ($399 for 58 markers), and Everlywell ($399 for 86 markers).
How much does a Homocysteine test cost at Quest Diagnostics?
At Quest Diagnostics, a Homocysteine test costs $81 on its own.
Is a Homocysteine test worth it?
Usually not, for the reason most people want it. Homocysteine got its reputation as a heart risk marker, but trials that lowered it with B vitamins didn't prevent heart attacks or strokes, which is why insurers and guidelines treat it as unproven for that purpose. It's genuinely useful in a workup for unexplained clots, a suspected B12 deficiency, or homocystinuria. As a general heart-health add-on, I'd spend the money on ApoB instead.
Either way, the price shouldn't be what decides it: Mito Health sells Homocysteine for $22 all-in. The cheapest panel that includes it is Parsley Health at $150–$275/mo, which is only worth it if you want the other 40 markers too.
Does insurance cover a Homocysteine test?
Insurance usually doesn't cover Homocysteine for screening. Major payers treat it as a screening test and deny it in people without symptoms, and Medicare doesn't cover screening either. When it is covered in-network, you pay about $20 to $35. If the claim is denied, the bill can run $145 to $600, which is why paying the $22 cash price outright is usually safer.
Aetna covers homocysteine for four things: borderline vitamin B12 deficiency, central retinal vein occlusion, homocystinuria, and a workup for unexplained or unusually early blood clots. Cardiovascular risk screening isn't on the list. The reason most people want a homocysteine test, gauging heart risk, is the one reason insurers won't pay for it.
The $27 allowed amount is an estimate, about 1.5x Medicare's $17.92 rate for CPT 83090, and it moves with the lab and the market: the same test is contracted around $18 at one national lab and into the $40s at another. Coinsurance is assumed at 20% once your deductible is met. Your own plan decides both, and most plans apply lab work to the deductible first, so the second outcome above is the one most people land on.
Homocysteine is billed as CPT 83090. That's the code to quote if you call your insurer to ask what you'd owe.
Frequently asked questions about Homocysteine testing
What is the cheapest way to get a Homocysteine test?
The cheapest Homocysteine test is $22–$28 at Mito Health. If you'd rather get more markers out of the same draw, Parsley Health's 41-biomarker panel is $150–$275/mo.
Do I need a doctor's order to get a Homocysteine test?
No. The standalone Homocysteine tests listed above include the physician order in their price, so you can buy online and have your blood drawn without seeing a doctor first. You'd only need your own doctor's order if you want to bill the test to insurance.
How much does a Homocysteine test cost at LabCorp?
LabCorp doesn't publish a flat consumer price for Homocysteine, and what you're charged varies by location. The cheapest way to have Homocysteine drawn at a LabCorp Patient Service Center is through DrSays, a LabCorp-network lab, at $43.98 all-in ($33.99 + $9.99 collection fee).
What is a normal homocysteine level?
A normal fasting homocysteine is roughly 5 to 15 micromol/L. Higher levels are linked to cardiovascular risk and often reflect low folate, vitamin B6, or B12.
Do I need to fast for a homocysteine test?
Yes. Homocysteine rises after eating, especially protein, so a 10 to 12 hour fast is recommended for an accurate measurement.